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Informatics Colloquium 17. 4. Virtual Reality Assessment for Examining Functional Neurological . . .Informatics Colloquium 17. 4. 2018, 14:00 lecture hall D2 doc. Fotios Liarokapis, Ph.D., FI MU Virtual Reality Assessment for Examining Functional Neurological Symptoms Abstract: Functional neurological symptoms (FNS) are somatic symptoms that still remain poorly understood. Their diagnosis is made by exclusion of organic cause and therefore does not provide any specific cues for the subsequent treatment. Virtual reality (VR) seems to be mature enough to be experimentally tested as a potential therapeutic intervention for the functional neurological disorders. Biofeedback is the process of gaining greater awareness of many physiological functions primarily using instruments that provide information on the activity of those same systems, with a goal of being able to manipulate them at will. Some of the processes that can be controlled include brainwaves, muscle tone, skin conductance, heart rate and pain perception. This presentation will evaluate immersive virtual reality as a potential therapeutic tool for a treatment of functional neurological symptoms. The first part will examine the effects of immersive virtual reality intervention on changes in autonomic arousal in FNS (in both healthy subjects and patients) by introducing emotional stress. The effect of immersion manipulation on changes in emotional reactivity to stress inducing stimuli is assessed by measuring skin conductance and heart rate variability. The second part will examine how biofeedback affects immersive virtual reality intervention on effective connectivity patterns in patients with FNS.