Přednáška pro odbornou veřejnost v rámci habilitačního řízení Ing. Vlada Popovici, M.Sc., Ph.D.
Jménem předsedy habilitační komise prof. Sochora si dovolujeme pozvat všechny
zájemce na přednášku pro odbornou veřejnost v rámci habilitačního řízení Ing.
Vlada Popovici, M.Sc., Ph.D. Přednáška pod názvem "Case studies in multimodal
biomarker discovery" bude proslovena v úterý 27. 3. 2018 od 14 hod v posluchárně
D2 v rámci informatického kolokvia.
Abstrakt přednášky:
High throughput genomic revolution started almost twenty years ago with the
first in-house printed DNA chips. Since then, various technologies evolved,
allowing the interrogation of the whole (human) genome, proteome, metabolome,
etc., all producing large amounts of data. Bioinformatics tools and methods
evolved to account for all these data modalities with the current bottleneck
being the integration of these perspectives into a more comprehensive picture.
In parallel and completely independent of bioinformatics, digital pathology also
witnessed significant advances fuelled mostly by technological developments:
slide scanners and computational infrastructure. However, both “classical”
bioinformatics and digital pathology/bioimaging are often used to investigate
the same biological phenomenon. It is, therefore, natural to attempt to combine
these two seemingly incompatible fields with the hope of unveiling new
connections between them. In this talk we will look at three examples of jointly
mining the transcriptome and the histopathology images in the context of breast
and colon cancers. We will also discuss the computational challenges one faces
when working with these data.