by Pavel Matula, Petr Matula, Michal Kozubek, October 2000, 14 pages.
FIMU-RS-2000-06. Available as Postscript, PDF.
This paper concerns fundamental tasks solved in the Laboratory of High-Resolution Cytometry in Brno and present and planned techniques for solving these tasks. The current research is aimed at 2-D and 3-D analysis of FISH-stained interphase nuclei, metaphase spreads and tissues. Both basic research and clinical applications are performed. The research is mostly performed using high-resolution cytometry technique developed in our laboratory. Two instruments capable of automated image acquisition from microscope slides have been developed. The acquired images are analysed by computer. The present image analysis system has some drawbacks. Therefore, development of a new system has started. The new system will be based on the client-server architecture and is called High-Resolution Cytometry Network.