To get to the centre of Prague from the airport, you can go by public transport or take a taxi.

Prague's public transport system offers the cheapest way to get from the airport to the centre and vice versa. Bus line 119 runs every 20 minutes between 4:00 and 24:00, leaving from a stop in front of the aiport terminal and going as far as the Dejvicka Metro station. (Before you get on the bus, you have to buy a 12 Kc ticket, available from vending machines or newsagents at the airport.) At the Dejvicka station you transfer to the Metro system and travel to either the Main Railway Station (Hlavni nadrazi) or the railway station Prague Holesovice, or to the central coach station at the Florenc Metro stop, depending on which means of transport you will be using to travel on to Brno (see below).

An alternative way of getting to the city centre is by taxi. There are flat rates of 380 Kc to the Holesovice railway station, 560 Kc to the central bus station Florenc, and approximately 650 Kc to destinations in the centre of the city (where the Main Railway Station is situated).

There is also the possibility of travelling directly to Brno from Prague airport on mini-buses operated by Czech Airlines. This service runs four times daily on weekdays and twice a day on weekends; the journey takes about 2 hours 45 minutes. It is best to make a reservation on this mini-bus when you buy your air ticket, but you can also enquire at the Czech Airlines desk at Prague airport as to whether there is a free seat on the next bus. If you have pre-booked a ticket on the mini-bus, you must "check in" at the Czech Airlines counter in the airport departure hall.